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  1. Genetic COPD - COPD Foundation

    Genetic COPD Alpha-1 antitrypsin deficiency (AATD) is the most common genetic factor associated with COPD, yet 90% of those affected remain undiagnosed. Early diagnosis of …

  2. COPD Causes and Risk Factors - American Lung Association

    Mar 19, 2025 · What Causes COPD? Over time, exposure to lung irritants like tobacco smoke or chemicals can damage your lungs and airways. This long-term exposure can cause chronic …