Leukocyte Esterase & Nitrites Basic Science The esterase method of detecting leukocytes in a urine sample relies on the fact that esterases are released from lysed urine granulocytes (neutrophils).

The specificity of urine nitrate is very high (more than 90%), so if the patient is nitrite positive, they clearly have a UTI.

Jul 14, 2025 · ED patients with positive leukocyte esterase and negative nitrite results on urinalysis are sevenfold more likely to have enterococcal UTI, a study finds.

Sep 2, 2024 · Compared with other methods, urine Gram stain moderately predicted gram-negative bacteria but added little value to UTI diagnosis in the ED, raising questions about its clinical utility.

Dipstick analysis detects the following: urine-specific gravity (USG), pH, leukocyte esterase, nitrites, protein, glucose, ketones, urobilinogen, bilirubin, blood and hemoglobin.

The urine drug concentration needed to show a positive result was 10 mg/L. Doxylamine intoxication resulted in false-positive results for both methadone and opiates when urine samples were checked ...

Urine microscopy is an important adjunct to the urinalysis. The findings of cells, casts or crystals can aid in urinalysis interpretation and in making a more accurate diagnosis. Since the formed ...

The creation of methemoglobinemia through the use of nitrites for cyanide poisoning entails some risk and, in particular, may be detrimental or even lethal to a patient with smoke inhalation and ...

Nov 18, 2025 · A novel urine biomarker identified significant differences in muscle health between menopausal and nonmenopausal women, based on data from 113 individuals. Menopause is known …

May 23, 2025 · The new infusion for maple syrup urine disease is for patients who cannot have an oral or enteral branched-chain amino acids-free formulation.